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The Lyapunov exponent plays a key role in the
2020-11-19
The Lyapunov exponent, plays a key role in the spectral analysis of the family . Here, S denotes the so-called Szegő transfer matrix, defined by Because the matrices so defined satisfy for , we have for . We define By general considerations, there is a compact set with for μ-a.e. . Moreover, by the
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Two additional hydrogen bonds are formed by the substituted
2020-11-19
Two additional hydrogen-bonds are formed by the -substituted methoxy-group with Ser and Asp. Ser exerts the role of a gate keeper in CK1: Entry of the ATP in the binding-site causes a conformational change into the closed form by Ser, which locks the binding-site and prevents ATP-diffusion out of th
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Lithium Citrate Therefore the relationship between ChEs acti
2020-11-19
Therefore, the relationship between ChEs activity and polymorphisms in POT1, TERF1, TERT genes were explored in order to screen susceptible biomarkers in this study. Materials and methods Results Discussion However, genetic toxicity induced by OPs has not been fully investigated so far. Ca
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It is common for plants that are deficient
2020-11-19
It is common for plants that are deficient in P to invest in their roots in order to maximise P uptake from the soil. Here, plants grown in soil amended with OA had a higher root biomass:shoot Fmoc-D-Phe(4-Cl)-OH ratio compared with plants in the INORG-P treatment. Additionally, greater allocation
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Raloxifene is a second generation SERM that has tissue
2020-11-19
Raloxifene is a second generation SERM that has tissue-specific effects that differ from those of tamoxifen. Raloxifene was marketed for prevention and treatment of osteoporosis in postmenopausal women in the US and Europe. In a phase II randomized double-blind study, tamoxifen and raloxifene were
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Progesterone s metabolite THP may also be mediating
2020-11-19
Progesterone's metabolite, 3α,5α-THP, may also be mediating burying and freezing responses. Results show female Long–Evans rats in behavioral estrous have higher P4 levels in serum, Silmitasertib and hippocampus compared to diestrous female Long–Evans rats. Additionally, ovx female Long–Evans rat ad
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br Experimental br Results and discussion On the basis of
2020-11-18
Experimental Results and discussion On the basis of the information obtained from the studies on RHA/TiO2 nanocomposites, it 4-ethylphenyl sulfate is expected that this reagent can be used as a catalyst for the promotion of the organic reactions. So this reagent was used in the promotion of th
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The defining molecular feature of
2020-11-18
The defining molecular feature of Ewing sarcoma is the characteristic EWSR1/ETS fusion protein, most commonly involving EWSR1 and FLI1 (Delattre et al., 1992, May et al., 1993). EWS–FLI1 causes global changes in gene expression both by directly regulating gene expression and by causing changes in ch
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Both progesterone and the calcium ionophore A rely on the
2020-11-18
Both progesterone and the calcium ionophore A23187 rely on the synthesis of cAMP by sAC to elicit exocytosis in human sperm (Fig. 2E-H and [8], [60]). We had reported earlier that digestion of endogenous cAMP with recombinant cAMP-specific phosphodiesterase 4D [9] or inhibition of its synthesis with
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To compare the phage of the th round
2020-11-18
To compare the phage of the 4th round results, we conducted isolated single rounds of FGE screening as described above for the 4 individual phage 4(1), 4(2), 4(3), and NC then determined the number of colony forming units afforded by cleavage from the support. Interestingly, we found that the 4(2) s
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br Materials and methods br Results Among probes the express
2020-11-18
Materials and methods Results Among 17,061 probes, the Bestatin of 758 probes (4.4%) showed at least a 2-fold upregulation (230 probes) or downregulation (528 probes) at day 3 after VMH lesioning as compared with sham-VMH lesioning. Supplement Table 1 shows the upregulated (>2-fold) and the do
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What are the molecular signals that guide Tfh cells
2020-11-18
What are the molecular signals that guide Tfh cells as they navigate around the lymph node in the course of the immune response? It was recently reported that Tfh cells inside GCs have high expression of SIPR2, which acts to repel them from the S1P-rich lymph in the SCS and promote their retention i
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The strand domain swap in the
2020-11-18
The β strand domain swap in the UbV.XR dimer appears to be a unique arrangement for a Ub-based dimer. In solution, free Ub has a KD of ∼5 mM for the monomer-dimer equilibrium, and the two subunits in the dimer adopt a range of relative orientations involving residues from Ub’s β sheet (Liu et al., 2
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A prominent example of such enzyme is the
2020-11-18
A prominent example of such enzyme is the proteasome, a highly promising target not only in cancer, but also in inflammatory and autoimmune diseases. Circulating proteasomes and respective anti-proteasome autoantibodies were detected in serum samples from patients with autoimmune diseases such as mu
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Despite the weak and transient nature of E E interactions
2020-11-18
Despite the weak and transient nature of E2–E3 interactions, this binding is required for the transfer of ubiquitin to the substrate. The low affinity characteristics of this interaction may be due to the fact that E2s use the same surface to interact with E1s and E3s, and hence while binding to an
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