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The pathophysiology underlying ONJ is unclear Decreased bone
2019-04-24
The pathophysiology underlying ONJ is unclear. Decreased bone remodeling induced by bisphosphonates or inhibition of osteoclast function, which interferes with healing of the microfractures and trauma occurring after dental extraction, have been hypothesized as potential mechanisms for ONJ, but thes
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br VIII Si atendemos a que Pablo del Prado en
2019-04-24
VIII. Si atendemos phosphodiesterase inhibitors que Pablo del Prado en su Directorio espiritual, todavía en el año de 1650, incorporaba numerosas oraciones para la comunión espiritual indígena, junto a recomendaciones sobre la exclusión de la efectiva, no parece probable que se alcanzara nunca un
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An interphase FISH analysis with BCR ABL DCDF dual
2019-04-24
An interphase FISH analysis with BCR-ABL1-DCDF (dual colour dual fusion) probes (Abbott) showed a normal signal pattern. In addition, an RT-PCR screen with primers specific for the BCR-ABL1 p210 and p190 fusion transcripts and a JAK2V617F mutation analysis were both negative. Chromosomal analysis of
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In the days before Christmas
2019-04-23
In the days before Christmas, 1952, adverse weather conditions and the burning of sulphurous coal led to the death of almost 12 000 people in London. Despite improvements in pollution prevention since the “Great Smog”, London continues to experience toxic air pollution linked to thousands of prematu
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A major development during was that
2019-04-23
A major development during 2015 was that OCV demand exceeded supply (). The main reasons for this increase in demand are the observed feasibility of mass OCV campaigns and their ability to confer protection to underserved populations in complex situations. The increased availability and use of OCV h
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br Conflict of interest br Introduction br
2019-04-23
Conflict of interest Introduction Case report Discussion Dextrocardia is commonly associated with situs inversus totalis (incidence: 2 in 10,000 individuals) and rarely associated with situs solitus (incidence: 1 in 20,000 individuals). While associated cardiac anomalies are seen in appr
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More recently primary tumor driven generation of a bone
2019-04-23
More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i
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br Autophagy and lipid metabolism LD formation is an
2019-04-23
Autophagy and lipid metabolism LD formation is an indispensable step in lipid metabolism. The Atg8/LC3 conjugation system is essential for autophagosome membrane formation. However, some evidence suggests that Atg8/LC3 conjugation is also involved in LD formation. Indeed, LD formation is suppress
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br The Global Burden of
2019-04-23
The Global Burden of Disease Study notes a substantial decrease in long-established global health threats such as communicable diseases and malnutrition, while underscoring the rise in non-communicable diseases and years lived with potentially disabling illnesses and injuries. One important but la
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br La historia de los animales
2019-04-23
La historia de los animales en el Nuevo Mundo La descripción de la notch inhibitor americana fue una tarea que realizaron algunos exploradores, soldados, funcionarios y religiosos como respuesta a la petición de información de las autoridades, deseosas de conocer la fauna y descubrir las propieda
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Y es que en Estados Unidos el campo
2019-04-23
Y es que, en Estados Unidos, el campo denominado Cultural Studies producía una gran cantidad de investigaciones sobre la región mediante categorías de análisis propias del llamado primer mundo. En su versión latinoamericana, los Estudios Culturales llegaron SEA0400 Supplier consolidarse en los años
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Chronic immunosuppression has been reported to
2019-04-23
Chronic immunosuppression has been reported to be linked with PEL [11]. Several patients with concomitant PEL and HIV infection were reported. Thus, a small portion of the elderly with immunosuppressive conditions may have a tendency to develop MALT lymphoma. Our elderly patient had no HIV infection
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We propose that the same geospatial statistical techniques c
2019-04-22
We propose that the same geospatial statistical techniques can be applied to HIV. We used these techniques to estimate the number of HIV-infected individuals in Maseru (a health-care district in Lesotho) and establish their geographical location. The district of Maseru is a relatively large area, ab
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Fischer and colleagues also raise concerns about
2019-04-22
Fischer and colleagues also raise concerns about the fact that MHSP “only offers testing to men”. As previously stated, MHSP is a public health programme based on the principles outlined in WHO\'s interim guidelines. The focus of that guidance is preventing sexual transmission of Ebola virus by men
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br Results There were patients younger than years of age
2019-04-22
Results There were 81 patients younger than 50 years of age who received 12 cores TRUSP biopsy at TPEVGH from January 2008 to December 2013. Four patients who received TRUSP biopsy for abnormal DRE or prostate sonography findings were excluded for PSA p-Cresyl sulfate group. There was no signific
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