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br Discussion Metastatic RCC is a fatal
2019-05-07
Discussion Metastatic RCC is a fatal disease with survival often measured in months, rather than years. Surgery alone is the standard of care for patients who present with isolated renal disease at the time of diagnosis. However, approximately 1/3 of these patients will go on to develop clinicall
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In conclusion we demonstrated that
2019-05-07
In conclusion, we demonstrated that diazoxide with the standard Ph had no detectable BCR–ABL1 KD mutations and that they were responsive to imatinib therapy, while cells with the variant translocation harbored two KD mutations, a previously described one and a never previously reported one [5]. The
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In Furman and Young were the
2019-05-07
In 1977, Furman and Young [3] were the first to report on transvenous pacemaker lead imidazoline in 12 children and adolescents. The youngest patient was 1 month old. After their report, several other papers on endocardial pacemaker implantation in small children were published (Table 2) [2,3,6–11]
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Roughly years have gone by since
2019-05-07
Roughly 15 years have gone by since the identification of the main characters involved in the interplay of the RANK–RANKL system. This gave rise to the race for elucidating their biological role . In those years, in vivo silencing experiments for both Receptor Activator of Nuclear Factor κ B (RANK)
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A quadripolar mapping catheter was placed along the RV septu
2019-05-07
A quadripolar mapping catheter was placed along the RV septum, and a 3.5mm bidirectional open irrigated mapping catheter (ThermoChool SF®, Biosense Webster, Johnson׳s & Johnson׳s, Diamond Bar, CA, US) was inserted retrogradely into the LV. An electroanatomical substrate map created using the CARTO3®
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The data obtained in our work
2019-05-07
The data obtained in our work showed that AMD was able to inhibit complex I activity and ATP biosynthesis in MRC-5 cells. These effects were accompanied by an increase in lipid and protein oxidative damage and a decrease in NO levels and superoxide dismutase and catalase activities, suggesting that
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Data for each assessment point are
2019-05-06
Data for each assessment point are expressed as the mean value plus standard deviation. One tailed paired t-tests were performed to analyze the effects of ibandronate treatment. Significance level was set at p Results The study included 33 patients with a variety of different primary tumors (Table
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br La profesionalizaci n del poeta como un perfil creador
2019-05-06
La profesionalización del poeta como un perfil creador La oferta sin precedentes que se ha experimentado en el terreno poético luego de varias iniciativas editoriales públicas y privadas en los años 1980-2010 (por ejemplo, Gabriel Bernal Granados o León Plascencia Ñol: 235) ha generado una bonan
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External parties ability and willingness to fund health inte
2019-05-06
External parties\' ability and willingness to fund health interventions is also an important factor in how governments decide on their spending priorities. Historically, development partners have funded prevention and treatment for a key group of diseases. Furthermore, a diverse set of barriers prev
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Vistos por lo tanto desde la ideolog
2019-05-06
Vistos, por lo tanto, desde la ideología revolucionaria ascendente, los marginales/campesinos conformaron, más que una presencia ciudadana, en sentido moderno, una especie de sensibilidad motivadora en la que se autorrecreaba una ontología de lo nacional. Esta fuerza fue muy importante en la articul
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br POR QU UNA PO TICA DEL EXILIO
2019-05-06
¿POR QUÉ UNA POÉTICA DEL EXILIO? A lo largo de nuestra investigación hemos seleccionado diversos autores y sus perspectivas que nos permiten analizar el objeto de estudio. Existe, por una parte, una dificultad por reconocer una problemática que atienda las necesidades de las producciones intelect
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Cabe mencionar que en despu s de
2019-05-06
Cabe mencionar que, en 2005, después de diez años de trabajar en la Universidad de Pittsburgh, espacio de gran relevancia para la gestación de las antologías analizadas, Moraña se trasladó lgk974 la Universidad de Washington en St. Louis, donde, hasta la fecha, pasó a fungir como profesora y directo
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To facilitate WHO s goals
2019-05-06
To facilitate WHO\'s goals, it buy PX-478 2HCl is important to assess the cost-effectiveness of interventions that incorporate emerging technologies for case detection, treatment, and vector control in the context of economic constraints and logistical barriers. In an elegant modelling study in , S
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Consequently in asymptomatic individuals multiple and
2019-05-06
Consequently, in asymptomatic individuals, multiple and repeated ECG recordings rather than drug testing are recommended for detecting the transient appearance of a spontaneous type 1 ECG, which may indicate the future development of arrhythmic events. Moreover, in addition recording at higher lead
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Introduction The assessment of hormonal receptor HR and
2019-05-05
Introduction The assessment of hormonal receptor (HR) and human epidermal growth factor receptor-2 (HER2) status by immunohistochemistry (IHC) groups breast cancer into three major subtypes: 1) luminal-like subtype (HR positive/HER2 negative); 2) HER2 subtype (HER2 positive and HR negative/positive
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