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br Conflict of interest br Acknowledgments This
2019-05-09
Conflict of interest Acknowledgments This research was supported by the Grants from the National Natural Science Foundation of China (No. 31270820 and No. 81230061 to Wei-Dong Han, No. 81402567 to Ya-jing Zhang) and was partially supported by a Grant from the National Basic Science and Develop
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Fig shows the percentage of patients with
2019-05-09
Fig. 2 shows the percentage of patients with high D-dimer levels in relation to the CHA2DS2–VASc scores and BNP levels. None of the patients had a CHA2DS2–VASc score of 0. The BNP levels were elevated in 3 (38%) of the 8 patients with CHA2DS2–VASc scores of 1, and the D-dimer levels were elevated in
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In this study we applied a more general approach along
2019-05-09
In this study, we applied a more general approach along these lines, which has previously been used only in few reports in the literature [8]. Based on a prospective BC database including all newly diagnosed BC cases at a large Swiss breast center over a 20-year period, we aimed to give a comprehens
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In addition to inducing IKs dysfunction through
2019-05-09
In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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La estructura del libro apuesta por
2019-05-09
La estructura del libro apuesta por plantear problemas, pero no por una solución única. De ahí que el desenlace de los capítulos previos sean dos re-flexiones distintas, pero complementarias: por un lado, la precaria fijación textual de un texto “condenado PyBOP cost existir en una forma que me gust
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Uno de los poemas extensos de
2019-05-09
Uno de los poemas extensos de Paz, que muestra con perfección esta poética de la estructuración espacial es “Vuelta”, publicado por primera vez, en forma suelta, al retorno del poeta order (-)-JQ1 México en 1971, e incluido después en el poemario de mismo nombre ( 1976). En unas de las páginas más n
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Premature deaths of women have profound effects
2019-05-08
Premature deaths of women have profound effects on families, societies, and economies, regardless of the age at which they occur and whatever the cause, including an—often preventable—NCD or injury later in life. Families, especially if female-headed, are driven into poverty through catastrophic hea
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The study reported high rates of antimicrobial resistance an
2019-05-08
The study reported high rates of antimicrobial resistance and also reminds us of the paucity of new drugs to treat such infections, especially in neonates, as well as the paucity of data on antimicrobial pharmacokinetics in this population. Observational and interventional multicentre studies are ne
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br The role of P in
2019-05-08
The role of P62 in tumors The role of P62 in osteoclastogenesis P62 as an oncotarget for treatment Concluding remarks P62 is a cellular “Swiss army knife,” with its diverse cellular functions arising from its unique functional motifs and protein–protein interaction properties. P62 may pl
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The majority of breast malignancies are
2019-05-08
The majority of breast malignancies are hormone responsive, and adjuvant endocrine therapy is used routinely to prevent breast cancer recurrence and death [6,7]. Tamoxifen was the past treatment of choice for endocrine-responsive postmenopausal breast cancer and was found to preserve BMD in postmeno
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Unfortunately no trends in retention
2019-05-07
Unfortunately, no trends in retention in care were presented by Nsanzimana and colleagues, and the method used to estimate life expectancy—the abridged life table method—is not well suited to answering questions about trends in quality of care, because it antimalaria medication allows little scope
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Esta autonom a junto a su prop sito de
2019-05-07
Esta autonomía, junto mglur antagonist su propósito de cambio social y su propuesta de una novedosa perspectiva sobre la política, convierte a los movimientos sociales en una particular fuente de conflicto, incluso en el contexto de estos países estudiados. La conflictividad es uno de los ejes prese
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br Descripci n de las variantes Las
2019-05-07
Descripción de las variantes Las variantes en los dos poemas estudiados a veces son leves: puntuación, acentuación o actualización de la ortografía. Pero cuando las acotaciones implican cambio de léxico o la sustitución de una parte o de un verso completo, constituyen un problema textual que ayud
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GP ablation has been regarded as a vagal denervation
2019-05-07
GP ablation has been regarded as a vagal denervation procedure that reduces the vagal tone in the atria and the vulnerability to AF. However, it is unclear how much vagal effect on the atrium is attenuated and how much of the atrium is denervated after the ablation. According to the GP mapping by Mc
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Clinical genetic electrocardiographic and electrophysiologic
2019-05-07
Clinical, genetic, electrocardiographic, and electrophysiological variables did not differ significantly between patients with and without the ER pattern (Table 2). Discussion Among our Brugada syndrome patients, the prevalence of the ER pattern was 10.1%, which is high in comparison to the 2%–5
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