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br ECM cancer and metastasis For cells to
2019-06-21
ECM, cancer and metastasis For p2y receptor to become cancerous they must acquire the ability to survive, grow and invade leading to malignant transformation, tumour formation and ultimately overt secondary metastasis. Abnormal ECM can promote these abilities and is a well-documented hallmark of
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Phosphorus is essential for organic activity such as cellula
2019-06-21
Phosphorus is essential for organic activity such as cellular signal transduction, membrane transport, mineral metabolism, and iMDK exchange [1]. Bone and teeth store 80% of the total body phosphorus. Intracellular phosphorus consists of the form of organic compounds such as adenosine triphosphate,
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A year old man was admitted
2019-06-21
A 49-year-old man was admitted to our hospital for SMVT treatment. He was diagnosed with DHCM at the age of 45 years in the referring hospital. His chief complaint was palpitations, and he was conscious and hemodynamically stable during the VT. A 12-lead electrocardiogram (ECG) during sinus rhythm r
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br Genetic basis for atrial standstill br
2019-06-21
Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an
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br Materials and methods br
2019-06-21
Materials and methods Results Discussion Conclusions Immediate ablation discontinuation during pulmonary vein isolation remarkably decreased the incidence of EsoTLs, even when using STS. EsoTL did occur after AFRA with immediate ablation discontinuation at the esophageal temperature prob
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Paying now rather than forever
2019-06-21
Paying now rather than forever has never been as relevant as a global health solution to the HIV pandemic than in 2013. The relative success of the ongoing replenishment session for the Global Fund is a positive signal, although still insufficient considering the evidence-based targets that are set
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Long marginalised as a disorder confined to specific
2019-06-21
Long marginalised as a disorder confined to specific racial groups, sickle-cell disease is now assuming its rightful place as a major global public health problem. Most patients in the Americas, the Caribbean, and much of Europe have been of one racial group, which led to the common misconception th
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This week delegates are gathered
2019-06-21
This week, delegates are gathered in Abu Dhabi, United Arab Emirates, for the . A large portion of the programme will be dedicated to global progress on demand reduction measures laid out in WHO\'s (FCTC), which celebrated its 10th birthday last month. Adopted at the 56th World Health Assembly in 20
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Respecto a estos ltimos el Papel
2019-06-21
Respecto a estos últimos, el Papel Periódico de la ciudad de Santafé de Bogotá (1791-1797) se constituyó en el órgano difusor de las discusiones adelantadas en la tertulia y se afirmó la necesidad de obtener la utilidad común y la contribución a la causa pública. En palabras de Renán Silva: Hasta e
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Outra implica o envolvida com
2019-06-21
Outra implicação envolvida com as os e que tem sido uma das principais bandeiras levantada por entidades contrárias é MRT68921 considerada terceirização da saúde pública. A terceirização foi assumida por alguns agentes envolvidos no processo, como o ex-secretário de saúde paulista e sanitarista José
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br The follow up clinic
2019-06-20
The follow-up clinic These trial results have significant implications for clinic efficiencies. The safe and effective replacement of the bulk of “routine” in-clinic evaluations demonstrated in TRUST (Fig. 3) has a huge implication for resource utilization. Although demanding adjustment to differ
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In the normal BMD subgroup there was progressive bone
2019-06-20
In the normal BMD subgroup, there was progressive bone loss over 3 years at the spine and hip (5.4% and 4.5%, respectively). This finding is consistent with the ATAC data [5]. Two patients required alendronate triggered by clinical events but there were no algorithm triggered events. There were no n
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In this study we analyzed the biological effects of
2019-06-20
In this study, we analyzed the biological effects of two novel GATA2 mutations, which were identified in adult de novo AML patients. Materials and methods The diagnosis of AML was based on the morphology, histopathology, the expression of leukocyte differentiation MRS 1220 and/or the French–Ame
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Introduction Leukaemias lymphomas and multiple myeloma can b
2019-06-20
Introduction Leukaemias, lymphomas and multiple myeloma can be the dreadful sequelae of viral infections. RNA oncogenic viruses, which are also known as retroviruses, were initially known to cause lymphoproliferative disorders only in animals, but have also been reported to demonstrate their transf
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br Discussion Case reports of successful chemotherapy desens
2019-06-20
Discussion Case reports of successful chemotherapy desensitizations have been described for platinum agents, taxanes, anthracyclines, rituximab [8], and cytarabine [9], but not specifically clofarabine. For older patients with relapsed AML that are not candidates to receive anthracycline therapy
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